Adult Cardiothoracic Surgery »  Education & Training »  Thoracic Fellows »  Johannes R. Kratz, M.D.

Johannes R. Kratz, M.D.

Thoracic Surgery Residency Program, 2017

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  • M.D. Harvard Medical School, Boston, MA., Magna cum laude, 2006
  • M.A. Stanford University, Palo Alto, CA., Philosophy, 2000
  • B.S. Stanford University, Palo Alto, CA., Biological Sciences (with Honors with Distinction), 1999
  • B.A. Stanford University, Palo Alto, CA.,Philosophy (with Distinction), 1999
  • 6/06-6/14           Resident, Department of General Surgery. Massachusetts General Hospital, Boston, MA.
  • Resident Research Fellow, UCSF Thoracic Oncology Lab, 2008-2011
  • Inflammation in lung tumorigenesis
  • Molecularly-targeted cancer therapies
  • Prognostic assays for early stage lung cancer

Johannes Kratz, M.D., was a research fellow in the Thoracic Oncology Lab from 2008-11. Dr. Kratz received his M.D. from Harvard Medical School, graduating Magna cum laude in 2006. He also holds a Masters in Philosophy from Stanford where he did his undergraduate work. Dr. Kratz is currently a Resident in the Department of General Surgery at Massachusetts General Hospital in Boston, MA.

Dr. Kratz played a pivotal role in the development of a prognostic assay for early-stage lung cancer patients, reported on in The Lancet and JAMA. The novel assay was validated in an international clinical trial led by a team of PIs that included thoracic surgeons David M. Jablons, M.D. and Michael Mann, M.D. The assay better predicted risk of death in early-stage lung cancer patients versus conventional staging guidelines and later successfully identified Stage 1A lung cancer patients who had a very high likelihood of mortality after surgery.

In addition to his translational work, Dr. Kratz conducted basic science research in the lab as part of a project studying inflammation and lung tumorigenesis.

Dr. Kratz has published fourteen peer-reviewed papers date, eight of them as first author, and has been the recipient of numerous awards and grants including the Partners Healthcare Resident/Fellow as Teacher Award, Willard M. Daggett Award, Edward Churchill Surgical Research Fellowship, Wyeth Scholarship of the American College of Surgeons, John E. Thayer Scholarship Award, Howard Hughes Medical Fellows Program Continued Support Award, Howard Hughes Medical Student Research Fellowship, and designation as a Soma Weiss Scholar.

Research Fellow, Thoracic Oncology Laboratory, University of California, San Francisco, Translational project involving the development and validation of a prognostic assay for early stage lung cancer and basic science project on the contribution of inflammation to lung tumorigenesis.

Research in Vascular Biology, Dr. Guillermo Garcia-Cardena, Brigham and Women's Hospital, Harvard Medical School, Boston, CA. The role of hemodynamic forces in the establishment and maintenance of blood vessel identity.

Most recent publications from a total of 19
  1. Shah JA, Patel MS, Kratz JR, Markmann JF, Vagefi PA.  High risk, high reward: An analysis of outcomes for candidates awaiting hepatic re-transplantation. Ann Hepatol. 2016 Nov-Dec 2016; 15(6):888-894. View in PubMed
  2. Hirata T, Zheng Q, Chen Z, Kinoshita H, Okamoto J, Kratz J, Li H, Lui N, Do H, Cheng T, Tseng HH, Koizumi K, Shimizu K, Zhou HM, Jablons D, He B. Wnt7A is a putative prognostic and chemosensitivity marker in human malignant pleural mesothelioma. Oncol Rep. 2015 Apr; 33(4):2052-60. View in PubMed
  3. Patel MS, Kohn R, Kratz JR, Shah JA, Markmann JF, Vagefi PA. The race to liver transplantation: a comparison of patients with and without hepatocellular carcinoma from listing to post-transplantation. J Am Coll Surg. 2015 Jun; 220(6):1001-7. View in PubMed
  4. Kohn R, Kratz JR, Markmann JF, Vagefi PA. The migrated liver transplantation candidate: insight into geographic disparities in liver distribution. J Am Coll Surg. 2014 Jun; 218(6):1113-8. View in PubMed
  5. Kratz JR, Tham PT, Mulvihill MS, Ziaei F, Ray MR, Hurst JW, Segal MR, Berryman DM, Chu W, He B, Jablons DM, Mann MJ. Analytical validation of a practical molecular assay prognostic of survival in nonsquamous non-small cell lung cancer. Diagn Mol Pathol. 2013 Jun; 22(2):65-9. View in PubMed
  6. Kratz JR, Mann MJ, Jablons DM. International trial of adjuvant therapy in high risk stage I non-squamous cell carcinoma identified by a 14-gene prognostic signature. Transl Lung Cancer Res. 2013 Jun; 2(3):222-5. View in PubMed
  7. Mann MJ, Jablons DM, Kratz JR. Prognostic assay in small, node-negative non-small cell lung cancer--reply. JAMA. 2013 Feb 27; 309(8):769-70. View in PubMed
  8. Mulvihill MS, Kratz JR, Pham P, Jablons DM, He B. The role of stem cells in airway repair: implications for the origins of lung cancer. Chin J Cancer. 2013 Feb; 32(2):71-4. View in PubMed
  9. Kratz JR, Van den Eeden SK, He J, Jablons DM, Mann MJ. A prognostic assay to identify patients at high risk of mortality despite small, node-negative lung tumors. JAMA. 2012 Oct 24; 308(16):1629-31. View in PubMed
  10. Choi H, Kratz J, Pham P, Lee S, Ray R, Kwon YW, Mao JH, Kang HC, Jablons D, Kim IJ. Development of a rapid and practical mutation screening assay for human lung adenocarcinoma. Int J Oncol. 2012 Jun; 40(6):1900-6. View in PubMed
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